Title: Top Mississippi County Hotels: 2026 Best Hotels in Mississippi County - Expedia.com [Vacation Rentals in Mississippi County](https://expedia.com/Destinations-In-Mississippi-County.d553248635976432543.Vacation-Rental-Destinations)[Mississippi County Flights](https://expedia.com/Destinations-In-Mississippi-County.d553248635976432543.Flight-Destinations)[Car Rentals in Mississippi County](https://expedia.com/Destinations-In-Mississippi-County.d553248635976432543.Car-Rental-Destinations)[Mississippi County Vacations](https://expedia.com/Mississippi-County.d553248635976432543.Destination-Travel-Guides) ![Hernando de Soto Bridge over the Mississippi River Memphis. It separates Tennessee from Arkansas, United States of America.](https://images.trvl-media.com/place/553248635976432543/a415ea8a-3196-45f9-80cd-79b265986557.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/553248635976432543/a415ea8a-3196-45f9-80cd-79b265986557.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Top Cities in Mississippi County ![](https://images.trvl-media.com/place/6058418/f75b8769-1e2b-4f05-8eee-e2245da6bc80.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Blytheville [](https://expedia.com/Blytheville-Hotels.d6058418.Travel-Guide-Hotels) ![Freight barge carrying cargo on Mississippi river, and Hernando deSoto bridge in Memphis, TN, USA](https://images.trvl-media.com/place/9048/a794aed8-86cd-4914-b7f8-daaf42ac360b.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Osceola [](https://expedia.com/Osceola-Hotels.d9048.Travel-Guide-Hotels) ![](https://images.trvl-media.com/place/553248635458706086/4e55dfb4-2868-49e3-a26d-ad99384ad470.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Dyess [](https://expedia.com/Dyess-Hotels.d553248635458706086.Travel-Guide-Hotels) ## Check prices for these dates Tonight [Apr 7 - Apr 8](https://www.expedia.com/Hotel-Search?regionId=553248635976432543&startDate=2026-04-07&endDate=2026-04-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Apr 8 - Apr 9](https://www.expedia.com/Hotel-Search?regionId=553248635976432543&startDate=2026-04-08&endDate=2026-04-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Apr 10 - Apr 12](https://www.expedia.com/Hotel-Search?regionId=553248635976432543&startDate=2026-04-10&endDate=2026-04-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Apr 17 - Apr 19](https://www.expedia.com/Hotel-Search?regionId=553248635976432543&startDate=2026-04-17&endDate=2026-04-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Mississippi County hotels ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/115000000/114390000/114380100/114380079/89abfba4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/115000000/114390000/114380100/114380079/2274ab65.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/115000000/114390000/114380100/114380079/ff17346b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/115000000/114390000/114380100/114380079/w3840h2158x0y0-52160e0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Osceola by IHG [](https://www.expedia.com/Osceola-Hotels-Holiday-Inn-Osceola-By-Ihg.h114380079.Hotel-Information) Osceola 8.6/10 Excellent (26 reviews) "Staff was courteous. Clean rooms. Restaurant was great." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Adrian $110 nightly $127 total May 8 - May 9 Total with taxes and fees [](https://www.expedia.com/Osceola-Hotels-Holiday-Inn-Osceola-By-Ihg.h114380079.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/50000/41800/41712/05343fb1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/41800/41712/00922bdc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/41800/41712/b4d3f15c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Two queens | In-room safe, desk, iron/ironing board, cribs/infant beds](https://images.trvl-media.com/lodging/1000000/50000/41800/41712/29810e3d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Blytheville [](https://www.expedia.com/Blytheville-Hotels-Hampton-Inn-Blytheville.h41712.Hotel-Information) Blytheville 9.2/10 Wonderful (916 reviews) "Great Staff, clean and quiet hotel. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Stuart $107 nightly $121 total Apr 15 - Apr 16 Total with taxes and fees [](https://www.expedia.com/Blytheville-Hotels-Hampton-Inn-Blytheville.h41712.Hotel-Information) ![Breakfast area](https://images.trvl-media.com/lodging/3000000/2040000/2032200/2032178/9e3a6143.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2040000/2032200/2032178/a88b7932.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2040000/2032200/2032178/54184826.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2040000/2032200/2032178/1f2bbf62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn & Suites Blytheville [](https://www.expedia.com/Blytheville-Hotels-Comfort-Inn-Suites.h2032178.Hotel-Information) Blytheville 8.6/10 Excellent (721 reviews) "This was a nice place to stay. Would recommend it to all." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tina $103 nightly $117 total May 8 - May 9 Total with taxes and fees [](https://www.expedia.com/Blytheville-Hotels-Comfort-Inn-Suites.h2032178.Hotel-Information) ![Louis 3 Bedroom Cottage A | Private kitchen | Mini-fridge, coffee/tea maker](https://images.trvl-media.com/lodging/94000000/93830000/93829900/93829832/4161dd61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Golf](https://images.trvl-media.com/lodging/94000000/93830000/93829900/93829832/3e2d6625.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/94000000/93830000/93829900/93829832/a7d05be5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/94000000/93830000/93829900/93829832/2473875f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Louis Hotel [](https://www.expedia.com/Wilson-Hotels-The-Louis-Hotel.h93829832.Hotel-Information) Wilson 9.6/10 Exceptional (61 reviews) "Staff was exceptional as was the accommodations. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael $219 nightly $245 total Apr 8 - Apr 9 Total with taxes and fees [](https://www.expedia.com/Wilson-Hotels-The-Louis-Hotel.h93829832.Hotel-Information) ![Indoor pool, seasonal outdoor pool, open 7 AM to 10 PM, pool umbrellas](https://images.trvl-media.com/lodging/1000000/10000/3400/3357/77afceed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Cocktail bar](https://images.trvl-media.com/lodging/1000000/10000/3400/3357/ccab0c81.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/3400/3357/a8aa83eb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, down comforters, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/10000/3400/3357/bd4e7635.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Blytheville by IHG [](https://www.expedia.com/Blytheville-Hotels-Holiday-Inn-Blytheville.h3357.Hotel-Information) Blytheville 8.4/10 Very Good (672 reviews) "Cleanliness, easy check in and out" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joseph $128 nightly $145 total Apr 12 - Apr 13 Total with taxes and fees [](https://www.expedia.com/Blytheville-Hotels-Holiday-Inn-Blytheville.h3357.Hotel-Information) ![Room, 2 Double Beds, Smoking | Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/88000000/87920000/87916900/87916825/dddaf316.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/88000000/87920000/87916900/87916825/4f0c811a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/88000000/87920000/87916900/87916825/1fa5848b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/88000000/87920000/87916900/87916825/6b6b4e27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Deerfield Inn By Capital O Blytheville AR I55 [](https://www.expedia.com/Blytheville-Hotels-Deerfield-Inn-By-Capital-O-Blytheville-AR-I55.h87916825.Hotel-Information) Blytheville 7.4/10 Good (74 reviews) "Stopped for the night due to fatigue. Check in and check out was smooth. Enjoyed a waffle and coffee before leaving. Good price for a good night of sleep." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kelly $61 nightly $68 total Apr 30 - May 1 Total with taxes and fees [](https://www.expedia.com/Blytheville-Hotels-Deerfield-Inn-By-Capital-O-Blytheville-AR-I55.h87916825.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1230000/1226700/1226644/c16d0cb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Double Beds, Non Smoking, Kitchenette | Down comforters, pillowtop beds, individually furnished, desk](https://images.trvl-media.com/lodging/2000000/1230000/1226700/1226644/a2571c3e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1230000/1226700/1226644/ba28dc3c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily full breakfast](https://images.trvl-media.com/lodging/2000000/1230000/1226700/1226644/79155d53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Americas Best Value Inn Suites & Studios Blytheville by Sonesta [](https://www.expedia.com/Blytheville-Hotels-Americas-Best-Value-Inn-Blytheville.h1226644.Hotel-Information) Blytheville 6.8/10 (437 reviews) "Roomy -clean- needs some upkeep but nice fir the price. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sandra $54 nightly $61 total Apr 18 - Apr 19 Total with taxes and fees [](https://www.expedia.com/Blytheville-Hotels-Americas-Best-Value-Inn-Blytheville.h1226644.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/9800/9746/beb06494.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/9800/9746/5ebfc8a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Individually decorated, individually furnished, desk, iron/ironing board](https://images.trvl-media.com/lodging/1000000/10000/9800/9746/db885cf0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Individually decorated, individually furnished, desk, iron/ironing board](https://images.trvl-media.com/lodging/1000000/10000/9800/9746/28e2aecc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Blytheville [](https://www.expedia.com/Blytheville-Hotels-Super-8-By-Wyndham-Blytheville.h9746.Hotel-Information) Blytheville 6.0/10 (532 reviews) "Room was clean. Staff was nice. Great for an overnight stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) William $57 nightly $65 total Apr 17 - Apr 18 Total with taxes and fees [](https://www.expedia.com/Blytheville-Hotels-Super-8-By-Wyndham-Blytheville.h9746.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/41700/41676/6e8f6961.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, free cribs/infant beds, rollaway beds, free WiFi](https://images.trvl-media.com/lodging/1000000/50000/41700/41676/927574bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/50000/41700/41676/d5c1715d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room amenity](https://images.trvl-media.com/lodging/1000000/50000/41700/41676/2481e426.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn & Suites by Wyndham Osceola AR [](https://www.expedia.com/Blytheville-Hotels-Days-Inn-Suites-By-Wyndham-Osceola-AR.h41676.Hotel-Information) Osceola 6.4/10 (381 reviews) "This was the worst hotel I have stayed at for at least 25 years. It was dirty, outdated. Staff seemed indifferent." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kim $64 nightly $74 total Apr 10 - Apr 11 Total with taxes and fees [](https://www.expedia.com/Blytheville-Hotels-Days-Inn-Suites-By-Wyndham-Osceola-AR.h41676.Hotel-Information) ![Single Room | Blackout drapes, soundproofing, free WiFi, bed sheets](https://images.trvl-media.com/lodging/122000000/121070000/121062600/121062570/ba85d102.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Microwave](https://images.trvl-media.com/lodging/122000000/121070000/121062600/121062570/2391c860.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/122000000/121070000/121062600/121062570/8cd0affc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Double Room | Blackout drapes, soundproofing, free WiFi, bed sheets](https://images.trvl-media.com/lodging/122000000/121070000/121062600/121062570/be90deef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairview Suites [](https://www.expedia.com/Blytheville-Hotels-Fairview-Suites.h121062570.Hotel-Information) Blytheville 6.8/10 (17 reviews) "Good place to stay for blue collar workers " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Scott $54 nightly $61 total Apr 27 - Apr 28 Total with taxes and fees [](https://www.expedia.com/Blytheville-Hotels-Fairview-Suites.h121062570.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/77000000/76940000/76930100/76930021/c6c2c410.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bathtub, hair dryer, towels](https://images.trvl-media.com/lodging/77000000/76940000/76930100/76930021/9b00666e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Single Room | Desk, free WiFi, bed sheets](https://images.trvl-media.com/lodging/77000000/76940000/76930100/76930021/26684060.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/77000000/76940000/76930100/76930021/825e07c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Roadside Inn [](https://www.expedia.com/Osceola-Hotels-Roadside-Inn.h76930021.Hotel-Information) Osceola 7.6/10 Good (29 reviews) "Good location, the room was large and the restaurant attached was very good." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Eric $53 nightly $61 total Apr 14 - Apr 15 Total with taxes and fees [](https://www.expedia.com/Osceola-Hotels-Roadside-Inn.h76930021.Hotel-Information) ![Business center](https://images.trvl-media.com/lodging/1000000/30000/20200/20128/ce00ef2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/30000/20200/20128/78179eba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, down comforters](https://images.trvl-media.com/lodging/1000000/30000/20200/20128/0fd71e28.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/30000/20200/20128/aff9a978.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Blytheville [](https://www.expedia.com/Blytheville-Hotels-Days-Inn-By-Wyndham-Blytheville.h20128.Hotel-Information) Blytheville 5.8/10 (387 reviews) "Nice hot breakfast. It was close to the expressway easy on and off" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kenneth $59 nightly $67 total Apr 27 - Apr 28 Total with taxes and fees [](https://www.expedia.com/Blytheville-Hotels-Days-Inn-By-Wyndham-Blytheville.h20128.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/121000000/120550000/120547600/120547558/7b08b617.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Double Room | Bathroom | Bathtub, towels, soap, shampoo](https://images.trvl-media.com/lodging/121000000/120550000/120547600/120547558/4a3b3bb5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/121000000/120550000/120547600/120547558/w924h613x1y0-dbf30dbf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/121000000/120550000/120547600/120547558/w921h613x0y0-276c63ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Sands Hotel [](https://www.expedia.com/Blytheville-Hotels-Sands-Hotel.h120547558.Hotel-Information) Blytheville 2.0/10 (1 review) $44 nightly $50 total Apr 27 - Apr 28 Total with taxes and fees [](https://www.expedia.com/Blytheville-Hotels-Sands-Hotel.h120547558.Hotel-Information) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/20000/15700/15679/4746c4b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Business center](https://images.trvl-media.com/lodging/1000000/20000/15700/15679/347725ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lunch and dinner served](https://images.trvl-media.com/lodging/1000000/20000/15700/15679/6034c339.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/1000000/20000/15700/15679/399d857f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Blytheville [](https://www.expedia.com/Blytheville-Hotels-Quality-Inn-Blytheville-I-55.h15679.Hotel-Information) Blytheville 6.6/10 (117 reviews) "Yes very nice staff." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Christopher [](https://www.expedia.com/Blytheville-Hotels-Quality-Inn-Blytheville-I-55.h15679.Hotel-Information) ![Private kitchen](https://images.trvl-media.com/lodging/123000000/122920000/122917200/122917109/8eb6cdab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/123000000/122920000/122917200/122917109/2826de7e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Smart TV](https://images.trvl-media.com/lodging/123000000/122920000/122917200/122917109/34d0f520.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/123000000/122920000/122917200/122917109/301a133d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tranquil 2-bedroom house with AC in charming Blytheville [](https://www.expedia.com/Blytheville-Hotels-Tranquil-2-Bedroom-House-With-AC-In-Charming-Blytheville.h122917109.Hotel-Information) Blytheville 8.8/10 Excellent (3 reviews) "House 10/10\. Neighborhood 3/10 but that’s not the host fault at all" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dekadra F. $238 nightly $268 total Apr 8 - Apr 9 Total with taxes and fees [](https://www.expedia.com/Blytheville-Hotels-Tranquil-2-Bedroom-House-With-AC-In-Charming-Blytheville.h122917109.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/113000000/112810000/112808700/112808687/4fcfe311.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/113000000/112810000/112808700/112808687/7a745300.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/113000000/112810000/112808700/112808687/ff129d50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/113000000/112810000/112808700/112808687/d5e7ae42.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The WrightWay Oasis. 3bedroom house 1bath with a fitness room, Wi-Fi an Smart Tv [](https://www.expedia.com/Blytheville-Hotels-Wright-Way-Oasis-3-Bedroom-House1-Bath-With-A-Fitness-Room.h112808687.Hotel-Information) Blytheville 8.6/10 Excellent (10 reviews) "The beds are very comfortable. Overall we felt it was a safe place to stay. Host was attentive and accommodating to our needs. Spacious for 9 women to stay in. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mi F. $272 nightly $306 total May 1 - May 2 Total with taxes and fees [](https://www.expedia.com/Blytheville-Hotels-Wright-Way-Oasis-3-Bedroom-House1-Bath-With-A-Fitness-Room.h112808687.Hotel-Information) ![Premium Room, 2 Double Beds, Kitchenette | Room amenity](https://images.trvl-media.com/lodging/24000000/23400000/23397300/23397288/98d458b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Room, 2 Double Beds, Kitchenette | Bathroom | Free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/24000000/23400000/23397300/23397288/w1275h1920x803y0-578f3e19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Room, 2 Double Beds, Kitchenette | Private kitchenette | Microwave, coffee/tea maker](https://images.trvl-media.com/lodging/24000000/23400000/23397300/23397288/61bc760e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium Room, 2 Double Beds, Kitchenette | Private kitchen | Microwave, coffee/tea maker](https://images.trvl-media.com/lodging/24000000/23400000/23397300/23397288/d45c4f5f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### OYO Hotel Blytheville AR I-55 [](https://www.expedia.com/Blytheville-Hotels-OYO-Hotel-Blytheville-AR-Hwy-61.h23397288.Hotel-Information) Blytheville 3.8/10 (130 reviews) "Cleanliness, staff & service, property conditions & facilities, room comfort, everything is excellent. Loved and enjoyed the stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mark [](https://www.expedia.com/Blytheville-Hotels-OYO-Hotel-Blytheville-AR-Hwy-61.h23397288.Hotel-Information) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/112000000/111540000/111531500/111531448/5b8972f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property grounds](https://images.trvl-media.com/lodging/112000000/111540000/111531500/111531448/6f99b3ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/112000000/111540000/111531500/111531448/eac776b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, desk, WiFi, bed sheets](https://images.trvl-media.com/lodging/112000000/111540000/111531500/111531448/40f6e371.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Mahase Guest House at The Refuge [](https://www.expedia.com/Mahase-Guest-House-At-The-Refuge.h111531448.Hotel-Information) Osceola 10/10 Exceptional (2 reviews) "Great place to stay! Quiet place and not too far from restaurants and market. Enjoyed the comfortable bed and the nice size kiitchen. I would definitely stay again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Alex b. [](https://www.expedia.com/Mahase-Guest-House-At-The-Refuge.h111531448.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/98000000/97160000/97150600/97150528/d34a5a6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/98000000/97160000/97150600/97150528/7c6132b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Living area](https://images.trvl-media.com/lodging/98000000/97160000/97150600/97150528/9cf1d3e1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/98000000/97160000/97150600/97150528/deeb824c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 3 bedrooms, 2 full bath, dining room, great room, den, beautiful outdoor patio. [](https://www.expedia.com/Blytheville-Hotels-3-Bedrooms.h97150528.Hotel-Information) Blytheville 10/10 Exceptional (18 reviews) "Perfect place for my crew and i to spend the week." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David M. [](https://www.expedia.com/Blytheville-Hotels-3-Bedrooms.h97150528.Hotel-Information) ![Desk, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/3000000/2410000/2400900/2400872/ff0baace.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/3000000/2410000/2400900/2400872/09ac7a55.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/tub, hair dryer, slippers, towels](https://images.trvl-media.com/lodging/3000000/2410000/2400900/2400872/10fcfbfb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/3000000/2410000/2400900/2400872/d6f1e2fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairview Suites [](https://www.expedia.com/Blytheville-Hotels-Fairview-Suites.h2400872.Hotel-Information) Blytheville 5.0/10 (54 reviews) "It was reasonable . Need more pillows on a king size bed. Everything else was good." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anonymous traveler [](https://www.expedia.com/Blytheville-Hotels-Fairview-Suites.h2400872.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-04-21&endDate=2026-04-22®ionId=553248635976432543&adults=2&sort=RECOMMENDED&openPlayBack=true) ## Great weekend hotel deals in Mississippi County, AR ### Showing deals for:**Apr 17 - Apr 19** ### Image gallery for Welcome to The Millionaire Palace!!!!!! ![Smart TV, fireplace, video games](https://images.trvl-media.com/lodging/109000000/108910000/108902700/108902695/6a357325.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Welcome to The Millionaire Palace!!!!!! Blytheville **10/10**Exceptional (2 reviews) 7% off $225 nightly $684 total Total with taxes and fees [](https://www.expedia.com/Hotel-Search?startDate=2026-04-17&endDate=2026-04-19&selected=108902695&adults=2) ### Image gallery for The WrightWay Oasis. 3bedroom house 1bath with a fitness room, Wi-Fi an Smart Tv ![Interior](https://images.trvl-media.com/lodging/113000000/112810000/112808700/112808687/4fcfe311.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### The WrightWay Oasis. 3bedroom house 1bath with a fitness room, Wi-Fi an Smart Tv Blytheville **8.6/10**Excellent (10 reviews) 7% off $189 nightly $565 total Total with taxes and fees [](https://www.expedia.com/Hotel-Search?startDate=2026-04-17&endDate=2026-04-19&selected=112808687&adults=2) ### Image gallery for Newly renovated family home in quiet neighborhood ![Interior](https://images.trvl-media.com/lodging/102000000/101250000/101240400/101240375/w904h683x59y0-b21017df.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Newly renovated family home in quiet neighborhood Blytheville **9.4/10**Exceptional (14 reviews) 6% off $144 nightly $480 total Total with taxes and fees [](https://www.expedia.com/Hotel-Search?startDate=2026-04-17&endDate=2026-04-19&selected=101240375&adults=2) ### Image gallery for Tranquil 2-bedroom house with AC in charming Blytheville ![Private kitchen](https://images.trvl-media.com/lodging/123000000/122920000/122917200/122917109/8eb6cdab.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Tranquil 2-bedroom house with AC in charming Blytheville Blytheville **8.8/10**Excellent (3 reviews) 12% off $120 nightly $451 total Total with taxes and fees [](https://www.expedia.com/Hotel-Search?startDate=2026-04-17&endDate=2026-04-19&selected=122917109&adults=2) ### Image gallery for Home Away From Home, Cozy Grounds, Minutes From the Excitements... ![Private kitchen](https://images.trvl-media.com/lodging/91000000/90290000/90289700/90289695/fd2bcfc3.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### Home Away From Home, Cozy Grounds, Minutes From the Excitements... Blytheville **8.6/10**Excellent (4 reviews) 7% off $203 nightly $597 total Total with taxes and fees [](https://www.expedia.com/Hotel-Search?startDate=2026-04-17&endDate=2026-04-19&selected=90289695&adults=2) ### Image gallery for The Louis Hotel ![Louis 3 Bedroom Cottage A | Private kitchen | Mini-fridge, coffee/tea maker](https://images.trvl-media.com/lodging/94000000/93830000/93829900/93829832/4161dd61.jpg?impolicy=fcrop&w=600&h=400&p=1&q=high) ### The Louis Hotel Wilson **9.6/10**Exceptional (61 reviews) 12% off $277 nightly $620 total Total with taxes and fees [](https://www.expedia.com/Hotel-Search?startDate=2026-04-17&endDate=2026-04-19&selected=93829832&adults=2) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Mississippi-County.d553248635976432543.Hotel-Destinations)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Mississippi-County.d553248635976432543.Hotel-Destinations) ## Top Mississippi County Hotel Reviews ![Hyatt Centric Beale Street Memphis](https://images.trvl-media.com/lodging/63000000/63000000/62999300/62999249/9dba71a9_y.jpg) ### Hyatt Centric Beale Street Memphis 10/10 Excellent "Accommodations were great! Loved the river view room and the rooftop lounge! The hotel staff were all very accommodating!! Would definitely stay at this property again!" [](https://expedia.com/Memphis-Hotels-Hyatt-Centric-Beale-Street-Memphis.h62999249.Hotel-Information) ![Big Cypress Lodge](https://images.trvl-media.com/lodging/13000000/13000000/12993400/12993388/dadd3c35_y.jpg) ### Big Cypress Lodge 10/10 Excellent "All around wonderful stay " [](https://expedia.com/Memphis-Hotels-Big-Cypress-Lodge.h12993388.Hotel-Information) ![Days Inn by Wyndham West Memphis](https://images.trvl-media.com/lodging/1000000/10000/1000/963/453d75d8_y.jpg) ### Days Inn by Wyndham West Memphis 2/10 Terrible "The room had bugs but the staff was friendly " [](https://expedia.com/Memphis-Hotels-Days-Inn-By-Wyndham-West-Memphis.h963.Hotel-Information) ![Hu. Hotel](https://images.trvl-media.com/lodging/1000000/810000/807600/807514/5be1c5b6_y.jpg) ### Hu. Hotel 8/10 Good "Very Clean Room" [](https://expedia.com/Memphis-Hotels-Hu-Hotel.h807514.Hotel-Information) ![ARRIVE Memphis](https://images.trvl-media.com/lodging/39000000/38950000/38941600/38941518/25133d44_y.jpg) ### ARRIVE Memphis 10/10 Excellent "In downtown Memphis, ARRIVE was a pleasant stay! I stayed in their suite and the staff were amazing. Everyone was so nice and the suite was great. " [](https://expedia.com/Memphis-Hotels-ARRIVE-Memphis.h38941518.Hotel-Information) ![Hampton Inn & Suites Memphis-Beale Street](https://images.trvl-media.com/lodging/1000000/460000/456300/456281/cd9e0fcf_y.jpg) ### Hampton Inn & Suites Memphis-Beale Street 10/10 Excellent "Rooms were clean " [](https://expedia.com/Memphis-Hotels-Hampton-Inn-Suites-Memphis-Beale-Street.h456281.Hotel-Information) ![Aloft Memphis Downtown](https://images.trvl-media.com/lodging/102000000/101850000/101840900/101840819/2fec4440_y.jpg) ### Aloft Memphis Downtown 10/10 Excellent "Great" [](https://expedia.com/Memphis-Hotels-Aloft-Memphis-Downtown.h101840819.Hotel-Information) ![Memphis Riverline Hotel](https://images.trvl-media.com/lodging/1000000/10000/900/821/758cde45_y.jpg) ### Memphis Riverline Hotel 2/10 Terrible "The staff stunk. Didn't know dry cleaning. Lost 3 dress articles trying to recover from trusting their dry cleaning promises. No bar no lobby coffee. Breakfast runner who didn't speak English. Sleepy security. TV didn't work. 5 bucks for a small bottle of water. Chip on shoulder front desk...and on and on shame because Sharon is a good brand" [](https://expedia.com/Memphis-Hotels-Sheraton-Memphis-Downtown-Hotel.h821.Hotel-Information) ![Hilton Garden Inn Memphis Downtown Beale Street](https://images.trvl-media.com/lodging/30000000/29150000/29143500/29143447/aaf2e52a_y.jpg) ### Hilton Garden Inn Memphis Downtown Beale Street 10/10 Excellent "Hotel was a great stay and great location. Really was in walking distance. The restaurant had good vibes and food " [](https://expedia.com/Memphis-Hotels-Hilton-Garden-Inn-Memphis-Downtown-TN.h29143447.Hotel-Information) ## Explore a world of travel with Expedia - Explore a world of travel with Expedia ### Top cities in Mississippi County - [Blytheville Hotels ](https://expedia.com/Blytheville-Hotels.d6058418.Travel-Guide-Hotels) - [Osceola Hotels ](https://expedia.com/Osceola-Hotels.d9048.Travel-Guide-Hotels) - [Wilson Hotels ](https://expedia.com/Wilson-Hotels.d553248635458701109.Travel-Guide-Hotels) - [Manila Hotels ](https://expedia.com/Manila-Hotels.d553248634999080581.Travel-Guide-Hotels) - [Joiner Hotels ](https://expedia.com/Joiner-Hotels.d553248634999254953.Travel-Guide-Hotels) - [Leachville Hotels ](https://expedia.com/Leachville-Hotels.d3000343188.Travel-Guide-Hotels) - [Dyess Hotels ](https://expedia.com/Dyess-Hotels.d553248635458706086.Travel-Guide-Hotels) - [Burdette Hotels ](https://expedia.com/Burdette-Hotels.d553248635975868572.Travel-Guide-Hotels) - [Luxora Hotels ](https://expedia.com/Luxora-Hotels.d553248635975867783.Travel-Guide-Hotels) - [Dell Hotels ](https://expedia.com/Dell-Hotels.d553248635975876297.Travel-Guide-Hotels) - [Etowah Hotels ](https://expedia.com/Etowah-Hotels.d6341249.Travel-Guide-Hotels) ### Hotels near popular Attractions - [Hotels near Johnny Cash House ](https://expedia.com/Johnny-Cash-House-Hotels.0-l553248621532648013-0.Travel-Guide-Filter-Hotels) - [Hotels near Delta Gateway Museum ](https://expedia.com/Delta-Gateway-Museum-Hotels.0-l553248634328751079-0.Travel-Guide-Filter-Hotels) - [Hotels near Arkansas Northeastern College ](https://expedia.com/Arkansas-Northeastern-College-Hotels.0-l6239816-0.Travel-Guide-Filter-Hotels) - [Hotels near Lights of the Delta ](https://expedia.com/Lights-Of-The-Delta-Hotels.0-l6274731-0.Travel-Guide-Filter-Hotels) - [Hotels near Arkansas Aeroplex ](https://expedia.com/Arkansas-Aeroplex-Hotels.0-l6274726-0.Travel-Guide-Filter-Hotels) - [Hotels near Walker Park ](https://expedia.com/Walker-Park-Hotels.0-l6239818-0.Travel-Guide-Filter-Hotels) - [Hotels near Riverlawn Country Club ](https://expedia.com/Riverlawn-Country-Club-Hotels.0-l553248635974650924-0.Travel-Guide-Filter-Hotels) - [Hotels near Thunder Bayou Golf Links ](https://expedia.com/Thunder-Bayou-Golf-Links-Hotels.0-l6239820-0.Travel-Guide-Filter-Hotels) - [Hotels near Hampson Archeological Museum State Park ](https://expedia.com/Hampson-Archeological-Museum-State-Park-Hotels.0-l553248621532648014-0.Travel-Guide-Filter-Hotels) ### More Accommodation Types in Mississippi County - [Vacation Homes in Mississippi County ](https://expedia.com/Mississippi-County-Private-Vacation-Homes.d553248635976432543-aaPrivateVacationHomes.Travel-Guide-Accommodation) - [Apartments in Mississippi County ](https://expedia.com/Mississippi-County-Apartments.d553248635976432543-aaApartments.Travel-Guide-Accommodation) - [Motels in Mississippi County ](https://expedia.com/Mississippi-County-Motels.d553248635976432543-aaMotels.Travel-Guide-Accommodation) - [Condo Rentals in Mississippi County ](https://expedia.com/Mississippi-County-Condos.d553248635976432543-aaCondos.Travel-Guide-Accommodation) - [Cottages in Mississippi County ](https://expedia.com/Mississippi-County-Cottages.d553248635976432543-aaCottages.Travel-Guide-Accommodation) - [Farmstay in Mississippi County ](https://expedia.com/Mississippi-County-Agritourism.d553248635976432543-aaAgritourism.Travel-Guide-Accommodation) - [Villas in Mississippi County ](https://expedia.com/Mississippi-County-Villas.d553248635976432543-aaVillas.Travel-Guide-Accommodation) - [Guest Houses in Mississippi County ](https://expedia.com/Mississippi-County-Guest-Houses.d553248635976432543-aaGuestHouses.Travel-Guide-Accommodation) - [Cabin Rentals in Mississippi County ](https://expedia.com/Mississippi-County-Cabins.d553248635976432543-aaCabins.Travel-Guide-Accommodation) - [Aparthotels in Mississippi County ](https://expedia.com/Mississippi-County-Apart-Hotels.d553248635976432543-aaApartHotels.Travel-Guide-Accommodation) - [B&B in Mississippi County ](https://expedia.com/Mississippi-County-Bed-And-Breakfast.d553248635976432543-aaBedAndBreakfast.Travel-Guide-Accommodation) ### Hotels near Mississippi County Airports - [Memphis Intl. Airport Hotels ](https://expedia.com/Memphis-Intl-Airport-Hotels.0-aMEM-0.Travel-Guide-Filter-Hotels) - [Jonesboro Municipal Airport Hotels ](https://expedia.com/Jonesboro-Municipal-Airport-Hotels.0-aJBR-0.Travel-Guide-Filter-Hotels) ### Popular national parks stays - [Hotels near Fort Pillow State Park ](https://www.expedia.com/Fort-Pillow-State-Park-Hotels.0-l553248621532655183-0.Travel-Guide-Filter-Hotels) ### Explore more hotels - [Hu. Hotel ](https://expedia.com/Memphis-Hotels-Hu-Hotel.h807514.Hotel-Information) - [Hyatt Centric Beale Street Memphis ](https://expedia.com/Memphis-Hotels-Hyatt-Centric-Beale-Street-Memphis.h62999249.Hotel-Information) - [Big Cypress Lodge ](https://expedia.com/Memphis-Hotels-Big-Cypress-Lodge.h12993388.Hotel-Information) - [The Peabody Memphis ](https://expedia.com/Memphis-Hotels-The-Peabody-Memphis.h15502.Hotel-Information) - [Comfort Inn Memphis Downtown ](https://expedia.com/Memphis-Hotels-Comfort-Inn-Memphis-Downtown.h12659.Hotel-Information) - [Memphis Riverline Hotel ](https://expedia.com/Memphis-Hotels-Sheraton-Memphis-Downtown-Hotel.h821.Hotel-Information) - [Aloft Memphis Downtown ](https://expedia.com/Memphis-Hotels-Aloft-Memphis-Downtown.h101840819.Hotel-Information) - [Hampton Inn & Suites Memphis-Beale Street ](https://expedia.com/Memphis-Hotels-Hampton-Inn-Suites-Memphis-Beale-Street.h456281.Hotel-Information) - [ARRIVE Memphis ](https://expedia.com/Memphis-Hotels-ARRIVE-Memphis.h38941518.Hotel-Information) - [The Westin Memphis Beale Street ](https://expedia.com/Memphis-Hotels-The-Westin-Memphis-Beale-Street.h1619507.Hotel-Information) [See a list of all hotels in Mississippi County](https://expedia.com/All-Mississippi-County-Hotels.d553248635976432543.Travel-Guide-City-All-Hotels) ### Expedia's Latest Trends Hotels - [Magic Springs and Crystal Falls hotels](https://expedia.com/Magic-Springs-And-Crystal-Falls-Hotels.0-l6070771-0.Travel-Guide-Filter-Hotels) - [Lake Ouachita State Park hotels](https://expedia.com/Lake-Ouachita-State-Park-Hotels.0-l553248635149794634-0.Travel-Guide-Filter-Hotels) - [University of Arkansas hotels](https://expedia.com/University-Of-Arkansas-Hotels.0-l6070783-0.Travel-Guide-Filter-Hotels) - [Crater of Diamonds State Park hotels](https://expedia.com/Crater-Of-Diamonds-State-Park-Hotels.0-l6070777-0.Travel-Guide-Filter-Hotels) - [Saracen Casino Resort hotels](https://expedia.com/Saracen-Casino-Resort-Hotels.0-l553248635998039781-0.Travel-Guide-Filter-Hotels) - [Hot Springs National Park hotels](https://expedia.com/Hot-Springs-National-Park-Hotels.0-l6070773-0.Travel-Guide-Filter-Hotels) - 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